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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A16
All Species:
18.48
Human Site:
T223
Identified Species:
27.11
UniProt:
P16260
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16260
NP_689920.1
332
36224
T223
V
G
L
S
H
A
P
T
L
L
G
R
P
S
S
Chimpanzee
Pan troglodytes
XP_001168284
332
36249
T223
V
G
L
S
H
A
P
T
L
L
G
R
P
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546134
332
36141
T223
V
G
L
S
H
A
P
T
L
L
G
R
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0K5
332
36201
A223
V
G
L
S
Y
A
P
A
L
L
G
R
P
S
S
Rat
Rattus norvegicus
P16261
322
35038
K217
F
F
T
F
G
T
L
K
S
V
G
L
S
Y
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520566
324
35638
T215
V
G
L
S
H
A
P
T
L
L
G
R
P
S
S
Chicken
Gallus gallus
XP_421570
320
35184
N211
I
G
L
A
Q
A
P
N
L
L
G
R
P
S
L
Frog
Xenopus laevis
Q5PQ27
327
36043
H221
L
K
K
L
H
A
E
H
S
G
R
T
Q
P
Y
Zebra Danio
Brachydanio rerio
Q0P483
321
35318
Y210
A
G
L
S
F
F
T
Y
E
T
L
K
K
T
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624199
316
35726
R209
Y
F
C
E
N
C
D
R
N
T
G
G
L
V
L
Nematode Worm
Caenorhab. elegans
Q20799
588
66319
T435
T
Y
V
R
Y
Y
E
T
N
S
S
E
P
G
V
Sea Urchin
Strong. purpuratus
XP_789697
271
30376
T166
A
S
F
Y
T
Y
E
T
A
K
I
F
L
L
T
Poplar Tree
Populus trichocarpa
XP_002308549
340
37252
S234
H
V
P
E
E
H
Q
S
I
V
M
R
L
S
C
Maize
Zea mays
P29518
436
46609
R318
L
Y
R
R
A
T
G
R
R
P
G
A
D
V
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_172908
331
36237
N225
H
V
P
E
E
H
Q
N
S
V
R
M
H
L
P
Baker's Yeast
Sacchar. cerevisiae
P38702
357
40807
A238
V
L
K
S
P
F
F
A
P
Y
S
V
L
E
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
96
N.A.
92.7
88.8
N.A.
82.5
81
37
38.2
N.A.
N.A.
50.2
20.2
39.7
Protein Similarity:
100
99.6
N.A.
98.1
N.A.
96.6
92.7
N.A.
87.9
86.7
54.2
53.9
N.A.
N.A.
62
31.6
53.6
P-Site Identity:
100
100
N.A.
100
N.A.
86.6
6.6
N.A.
100
66.6
13.3
20
N.A.
N.A.
6.6
13.3
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
20
N.A.
100
80
20
33.3
N.A.
N.A.
13.3
26.6
13.3
Percent
Protein Identity:
34.4
21.7
N.A.
37.9
37.5
N.A.
Protein Similarity:
54.4
34.8
N.A.
53.6
55.1
N.A.
P-Site Identity:
13.3
6.6
N.A.
0
13.3
N.A.
P-Site Similarity:
33.3
13.3
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
7
7
44
0
13
7
0
0
7
0
0
7
% A
% Cys:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
0
0
7
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
19
13
0
19
0
7
0
0
7
0
7
0
% E
% Phe:
7
13
7
7
7
13
7
0
0
0
0
7
0
0
0
% F
% Gly:
0
44
0
0
7
0
7
0
0
7
57
7
0
7
7
% G
% His:
13
0
0
0
32
13
0
7
0
0
0
0
7
0
7
% H
% Ile:
7
0
0
0
0
0
0
0
7
0
7
0
0
0
0
% I
% Lys:
0
7
13
0
0
0
0
7
0
7
0
7
7
0
0
% K
% Leu:
13
7
44
7
0
0
7
0
38
38
7
7
25
13
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
7
0
0
0
% M
% Asn:
0
0
0
0
7
0
0
13
13
0
0
0
0
0
0
% N
% Pro:
0
0
13
0
7
0
38
0
7
7
0
0
44
7
7
% P
% Gln:
0
0
0
0
7
0
13
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
7
13
0
0
0
13
7
0
13
44
0
0
0
% R
% Ser:
0
7
0
44
0
0
0
7
19
7
13
0
7
44
32
% S
% Thr:
7
0
7
0
7
13
7
38
0
13
0
7
0
7
7
% T
% Val:
38
13
7
0
0
0
0
0
0
19
0
7
0
13
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
13
0
7
13
13
0
7
0
7
0
0
0
7
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _